ANALYSIS OF THE BOVINE HERPESVIRUS TYPE-1 THYMIDINE KINASE (TK) GENE FROM WILD-TYPE VIRUS AND TK-DEFICIENT MUTANTS

被引：66

作者：

MITTAL, SK ^{[1
]}

FIELD, HJ ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,DEPT CLIN VET MED,MADINGLEY RD,CAMBRIDGE CB3 0ES,ENGLAND

来源：

JOURNAL OF GENERAL VIROLOGY | 1989年 / 70卷

关键词：

D O I：

10.1099/0022-1317-70-4-901

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：901 / 918

页数：18

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[22] Intracellular uptake of thymidine and antiherpetic drugs for thymidine kinase-deficient mutants of herpes simplex virus type 1 [J].

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[23] MOLECULAR ANALYSIS OF THE THYMIDINE KINASE GENE OF THYMIDINE KINASE-DEFICIENT MUTANTS OF VARICELLA-ZOSTER VIRUS [J].

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[24] THE UTILIZATION OF TRIFLUOROTHYMIDINE (TFT) TO SELECT FOR THYMIDINE KINASE-DEFICIENT (TK-(-)-) MUTANTS FROM L5178Y-TK+/- MOUSE LYMPHOMA-CELLS [J].

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[25] LOCATION AND CHARACTERIZATION OF THE BOVINE HERPESVIRUS TYPE 4 THYMIDINE KINASE GENE - COMPARISON WITH THYMIDINE KINASE GENES OF OTHER HERPESVIRUSES [J].

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[26] Analysis of mutations at the adenine phosphoribosyl-transferase gene locus in wild-type and thymidine kinase-deficient Friend cells. [J].

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[27] The immune response to vaccinia virus is significantly reduced after scarification with TK- recombinants as compared to wild-type virus [J].

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[28] RATIONAL APPROACH TO DEVELOPMENT OF ANTIVIRAL CHEMOTHERAPY - ALTERNATIVE SUBSTRATES OF HERPES-SIMPLEX VIRUS TYPE-1 (HSV-1) AND TYPE-2 (HSV-2) THYMIDINE KINASE (TK) [J].

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[30] Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase [J].

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