THERAPEUTIC EFFECT OF PERCUTANEOUS ETHANOL INJECTION ON SMALL HEPATOCELLULAR-CARCINOMA - EVALUATION WITH CT

被引:92
作者
EBARA, M [1 ]
KITA, K [1 ]
SUGIURA, N [1 ]
YOSHIKAWA, M [1 ]
FUKUDA, H [1 ]
OHTO, M [1 ]
KONDO, F [1 ]
KONDO, Y [1 ]
机构
[1] CHIBA UNIV,SCH MED,DEPT PATHOL 2,CHUO KU,CHIBA 260,JAPAN
关键词
ALCOHOL; LIVER; CT; LIVER NEOPLASMS; THERAPY;
D O I
10.1148/radiology.195.2.7536946
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
PURPOSE: To evaluate the therapeutic effect of percutaneous ethanol injection (PEI) on small hepatocellular carcinoma (HCC) with computed tomography (CT). MATERIALS AND METHODS: Sixty-seven patients with histologically proved HCC 3 cm or less in diameter underwent PEI. The patients were regularly followed up with sonography and contrast material-enhanced CT for more than 1 year (range, 12-96 months). The CT findings were evaluated for three tumor types distinguished on the basis of their appearance relative to that of the surrounding liver parenchyma: type 1 = hyperattenuating at the early phase (n = 39), type 2 = iso- or hypoattenuating at the early phase and hypoattenuating at the late phase (n = 18), and type 3 = isoattenuating (not detected) at both the early and late phases (n = 10). RESULTS: After PEI, a necrotic area of HCC and the surrounding liver parenchyma was characterized as hypoattenuating at both early and late phases of contrast-enhanced CT, regardless of the type. When an HCC appeared to be completely necrotic within 3 months after PEI, this status was retained until the latest observation in all but three cases. CONCLUSION: Contrast-enhanced CT can correctly depict PEI-induced necrosis in HCC and is reliable for evaluating the therapeutic effect of PEI.
引用
收藏
页码:371 / 377
页数:7
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