PRODUCTION OF BABOON (PAPIO-HAMADRYAS) MONOCLONAL-ANTIBODIES BY HERPESVIRUS PAPIO IMMORTALIZED BABOON LYMPH-NODE CELLS

被引：4
作者：
SHARP, RM
DUROCHER, CL
PARMENTER, JL
机构：
[1] Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio
来源：
JOURNAL OF IMMUNOLOGICAL METHODS | 1990年 / 126卷 / 02期
关键词：
(Baboon); (Macaque); (Monkey); (Papio); (Primate); Apolipoprotein B; Autoantibody; Epstein-Barr virus; Low density lipoprotein; Monoclonal antibody;
D O I：
10.1016/0022-1759(90)90162-O
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Baboon monoclonal antibodies specific for monomorphic determinants of baboon apolipoprotein B were produced from in vivo primed lymph node cells immortalized by herpesvirus papio (HVP). Two cell lines from the immortalized cells were readily stabilized and grew rapidly. Since Epstein-Barr virus (EBV) cannot be used to immortalize baboon or macaque cells, HVP expands the potential sources of monoclonal antibodies to include baboons, and is the immortalizing agent of choice for macaques as well. © 1990.
引用
收藏
页码：287 / 294
页数：8
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