AUTOMATIC DETECTION OF SPONTANEOUS SYNAPTIC RESPONSES IN CENTRAL NEURONS

被引：86

作者：

ANKRI, N

LEGENDRE, P

FABER, DS

KORN, H

机构：

[1] INST PASTEUR,DEPT BIOTECHNOL,NEUROBIOL CELLULAIRE LAB,INSERM,U261,F-75724 PARIS 15,FRANCE

[2] MED COLL PENN,DEPT ANAT & NEUROBIOL,PHILADELPHIA,PA 19129

来源：

JOURNAL OF NEUROSCIENCE METHODS | 1994年 / 52卷 / 01期

基金：

美国国家卫生研究院;

关键词：

SIGNAL ANALYSIS; AUTOMATIC DETECTION; AUTOMATIC MEASUREMENT; TEMPLATE RECOGNITION; SYNAPTIC NOISE; QUANTUM; SIMULATED SPONTANEOUS ACTIVITY;

D O I：

10.1016/0165-0270(94)90060-4

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A fully automatized software package for detection and measurements of randomly occurring synaptic transients embedded in background noise is described. It is based on waveform recognition protocols, allows analysis of long data segments, and provides quantitative information about event amplitudes and kinetics. Simulated postsynaptic recordings have been used to assess its performance over a wide range of conditions mimicking those seen in physiological experiments.

引用

页码：87 / 100

页数：14

共 18 条

[1] ORIGIN OF VARIABILITY IN QUANTAL SIZE IN CULTURED HIPPOCAMPAL-NEURONS AND HIPPOCAMPAL SLICES [J].