LYSOPHOSPHATIDIC ACID SIGNALING

被引：222
作者：
MOOLENAAR, WH
机构：
[1] Division of Cellular Biochemistry, The Netherlands Cancer Institute, 1066 CX Amsterdam
来源：
CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 02期
关键词：
D O I：
10.1016/0955-0674(95)80029-8
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Lysophosphatidic acid is an intercellular phospholipid messenger that is released from platelets (and probably other cells) and evokes multiple biological responses, ranging from induction of mitogenesis to neurite retraction, by activating a specific G protein coupled receptor. Recent studies indicate that the lysophosphatidic acid receptor acts via the smalt GTP-binding proteins Ras and Rho to stimulate cell proliferation and to trigger actin-based cytoskeletal events, respectively.
引用
收藏
页码：203 / 210
页数：8
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