EFFICIENT SYNTHESES OF NEW CLASSES OF REGIOCHEMICALLY PURE BENZOPORPHYRIN DERIVATIVES

被引：15

作者：

PANDEY, RK ^{[1
]}

JAGEROVIC, N ^{[1
]}

RYAN, JM ^{[1
]}

DOUGHERTY, TJ ^{[1
]}

SMITH, KM ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,DEPT CHEM,DAVIS,CA 95616

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 12期

关键词：

D O I：

10.1016/S0960-894X(01)80726-5

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Starting from rhodoporphyrin-XV dimethyl ester 4 and phylloerythrin methyl ester 5 new classes of isomerically pure benzoporphyrin analogues 7, 8, 11-17 were synthesized in high yields. These compounds have strong long wavelength absorptions in the red region and demonstrate activity against a transplanted mouse tumor.

引用

页码：2615 / 2618

页数：4

共 13 条

[1] ADDITIONS TO PORPHINS INVOLVING FORMATION OF NEW CARBON-CARBON BONDS
CALLOTT, HJ
JOHNSON, AW
SWEENEY, A
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (13): : 1424 - 1427
[2] REACTIONS OF PROTOPORPHYRIN WITH TETRACYANOETHYLENE
DINELLO, RK
DOLPHIN, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1980, 45 (25) : 5196 - 5204
[3] NEW SYNTHESES OF BENZOPORPHYRIN DERIVATIVES AND ANALOGS FOR USE IN PHOTODYNAMIC THERAPY
MEUNIER, I
PANDEY, RK
WALKER, MM
SENGE, MO
DOUGHERTY, TJ
SMITH, KM
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1992, 2 (12) : 1575 - 1580
[4] READY SYNTHESES OF BENZOPORPHYRINS VIA DIELS-ALDER REACTIONS WITH PROTOPORPHYRIN-IX
MORGAN, AR
PANGKA, VS
DOLPHIN, D
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1984, (16) : 1047 - 1048
[5] CHLORIN AND PORPHYRIN DERIVATIVES AS POTENTIAL PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY
PANDEY, RK
BELLNIER, DA
SMITH, KM
DOUGHERTY, TJ
[J]. PHOTOCHEMISTRY AND PHOTOBIOLOGY, 1991, 53 (01) : 65 - 72
[6] STRUCTURE-ACTIVITY-RELATIONSHIPS AMONG PHOTOSENSITIZERS RELATED TO PHEOPHORBIDES AND BACTERIOPHEOPHORBIDES
PANDEY, RK
SHIAU, FY
SUMLIN, AB
DOUGHERTY, TJ
SMITH, KM
[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1992, 2 (05) : 491 - 496
[7] LONG WAVELENGTH PHOTOSENSITIZERS RELATED TO CHLORINS AND BACTERIOCHLORINS FOR USE IN PHOTODYNAMIC THERAPY
PANDEY, RK
SHIAU, FY
RAMACHANDRAN, K
DOUGHERTY, TJ
SMITH, KM
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1992, (11): : 1377 - 1385
[8] PORPHYRIN DIMERS AS PHOTOSENSITIZERS IN PHOTODYNAMIC THERAPY
PANDEY, RK
SMITH, KM
DOUGHERTY, TJ
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (07) : 2032 - 2038
[9] PANDEY RK, 1989, SPIE P, V1065, P164
[10] RICHTER AM, 1990, JNCI-J NATL CANCER I, V52, P501

← 1 2 →