NOVEL CAGE-TYPE AZAPARACYCLOPHANE BEARING CHIRAL BINDING-SITES

被引：36

作者：

MURAKAMI, Y

OHNO, T

HAYASHIDA, O

HISAEDA, Y

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 14期

关键词：

D O I：

10.1039/c39910000950

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The guest-binding behaviour of a novel cage-type azaparacyclophane, which has been prepared by the reaction of N,N',N'',N'''-tetravalyl-1,6,20,25-tetraaza[6.1.6.1]paracyclophane with N,N',N'',N'''-tetrakis(5-carboxynicotinoyl)-2,11,20,29-tetraaza[3.3.3.3]paracyclophane, was examined in aqueous media and evaluated by a computer-aided molecular modelling study on the basis of molecular mechanics (MM2 and MMP2) and molecular dynamics (AMBER and CHARMM) conformational search.

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页码：950 / 952

页数：3

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