METHIONINE AND HISTIDINE PD(II) AND PT(II) COMPLEXES - CRYSTAL-STRUCTURES AND SPECTROSCOPIC PROPERTIES

X-ray crystal structures and properties of the two Pd(II) complexes, [Pd(L-methionine)Cl2] and [Pd(L-histidine)Cl2] and the properties of the corresponding complexes of Pt(II) are described. The amino acids are bound to the metal ion by N (from the NH2 group) and by S in the case of the methionine, or N (from the imidazolic group) in the case of the histidine. Reactions of these compounds with nucleotides have been studied and found to yield several ternary compounds with 5'-GMP and 5'-IMP. In all cases, the Cl ion has been replaced by one molecule of nucleotide. The metal ion seems to be coordinated to the N(7) atom of the 5'-GMP purine ring and to the N(7) or N(3) of the 5'-IMP purine ring.