CORTISOL AND BETA-ENDORPHIN RESPONSES TO SLEEP-DEPRIVATION IN MAJOR DEPRESSION - THE HYPERAROUSAL THEORIES OF SLEEP-DEPRIVATION

被引：12
作者：
EBERT, D
KASCHKA, WP
LOEW, T
BECK, G
机构：
[1] Psychiatrische Klinik, Universitat Erlangen-Nurnberg, D-91054 Erlangen
来源：
NEUROPSYCHOBIOLOGY | 1994年 / 29卷 / 02期
关键词：
MAJOR DEPRESSION; SLEEP DEPRIVATION; CORTISOL; BETA-ENDORPHIN; HYPERAROUSAL; STRESS;
D O I：
10.1159/000119066
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
To test theories that response to sleep deprivation in depression is the result of either stress reactions or down-regulation of hyperarousal, the early morning cortisol and beta-endorphin levels of depressed sleep deprivation responders and nonresponders before and after sleep deprivation were compared (areas under the curve of 8 blood samples between 7.30 and 10 a.m.). The beta-endorphin response was significantly different in responders and nonresponders, whereas all other comparisons remained nonsignificant. The results do not support theories that sleep deprivation acts as a stressor, but are not contradictory to the hyperarousal hypothesis of sleep deprivation.
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收藏
页码：64 / 68
页数：5
相关论文
共 37 条
[1]   DEPRESSION - THE PREDISPOSING INFLUENCE OF STRESS [J].
ANISMAN, H ;
ZACHARKO, RM .
BEHAVIORAL AND BRAIN SCIENCES, 1982, 5 (01) :89-99
[2]   NEUROENDOCRINOLOGICAL INVESTIGATIONS DURING SLEEP-DEPRIVATION IN DEPRESSION .1. EARLY MORNING LEVELS OF THYROTROPIN, TH, CORTISOL, PROLACTIN, LH, FSH, ESTRADIOL, AND TESTOSTERONE [J].
BAUMGARTNER, A ;
GRAF, KJ ;
KURTEN, I ;
MEINHOLD, H ;
SCHOLZ, P .
BIOLOGICAL PSYCHIATRY, 1990, 28 (07) :556-568
[3]   NEUROENDOCRINOLOGICAL INVESTIGATIONS DURING SLEEP-DEPRIVATION IN DEPRESSION .2. LONGITUDINAL MEASUREMENT OF THYROTROPIN, TH, CORTISOL, PROLACTIN, GH, AND LH DURING SLEEP AND SLEEP-DEPRIVATION [J].
BAUMGARTNER, A ;
RIEMANN, D ;
BERGER, M .
BIOLOGICAL PSYCHIATRY, 1990, 28 (07) :569-587
[4]  
Bertolucci P H, 1987, Arq Neuropsiquiatr, V45, P224
[5]   EFFECTS OF TOTAL SLEEP-DEPRIVATION ON URINARY CORTISOL, SELF-RATED AROUSAL, AND MOOD IN DEPRESSED-PATIENTS [J].
BOUHUYS, AL ;
FLENTGE, F ;
VANDENHOOFDAKKER, RH .
PSYCHIATRY RESEARCH, 1990, 34 (02) :149-162
[6]   OBSERVED BEHAVIOR AS A PREDICTOR OF THE RESPONSE TO SLEEP-DEPRIVATION IN DEPRESSED-PATIENTS [J].
BOUHUYS, AL ;
BEERSMA, DGM ;
VANDENHOOFDAKKER, RH .
PSYCHIATRY RESEARCH, 1989, 28 (01) :47-61
[7]   EFFECTS OF SLEEP-DEPRIVATION ON THE LIMBIC SYSTEM AND THE FRONTAL LOBES IN AFFECTIVE-DISORDERS - A STUDY WITH TC-99M-HMPAO SPECT [J].
EBERT, D ;
FEISTEL, H ;
BAROCKA, A .
PSYCHIATRY RESEARCH-NEUROIMAGING, 1991, 40 (04) :247-251
[8]  
EBERT D, 1992, FORTSCHR NEUROL PSYC
[9]  
EBERT D, IN PRESS EUR PSYCHIA
[10]   BIOLOGICAL AND BEHAVIORAL-EFFECTS OF ONE NIGHTS SLEEP-DEPRIVATION IN DEPRESSED-PATIENTS AND NORMALS [J].
GERNER, RH ;
POST, RM ;
GILLIN, C ;
BUNNEY, WE .
JOURNAL OF PSYCHIATRIC RESEARCH, 1979, 15 (01) :21-40
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