TRANSIENT NEONATAL DIABETES-MELLITUS - A RELAPSE AFTER 10 YEARS OF COMPLETE REMISSION

被引：5

作者：

VANELLI, M

DEFANTI, A

CANTONI, S

CHIARI, G

机构：

[1] Department of Pediatrics, Diabetes Unit, University of Parma, Parma

来源：

ACTA DIABETOLOGICA | 1994年 / 31卷 / 02期

关键词：

NEONATAL DIABETES MELLITUS; INFANT; INSULIN-DEPENDENT DIABETES MELLITUS; INSULIN-LIKE GROWTH FACTOR I (IGF-I); GROWTH;

D O I：

10.1007/BF00570547

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The follow-up study of a patient with permanent diabetes (DM) unrelated to islet cell antibody and anti-insulin antibodies and occurring 10 years after a transient neonatal DM episode is reported. A latent defect in insulin release was proved. It produced transient glucosuria during intercurrent illnesses and permanent hyperglycaemia and a decrease in growth velocity [with high stimulated growth hormone and low insulin-like growth factor I (IGF-I)] at the onset of puberty. After insulin therapy was re-introduced, catch-up growth and normalization of the blood glucose and IGF-I levels were noted.

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收藏

页码：116 / 118

页数：3

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