Management of conjunctival malignant melanoma: a review and update

被引：122

作者：

Wong, James R. ^{[1
]}

Nanji, Afshan A. ^{[1
]}

Galor, Anat ^{[1
,2
]}

Karp, Carol L. ^{[1
]}

机构：

[1] Univ Miami, Miller Sch Med, Bascom Palmer Eye Inst, 900 NW 17th St, Miami, FL 33136 USA

[2] Miami Vet Affairs Med Ctr, Dept Ophthalmol, Miami, FL USA

来源：

EXPERT REVIEW OF OPHTHALMOLOGY | 2014年 / 9卷 / 03期

关键词：

BRAF inhibitors; conjunctival malignant melanoma; dabrafen ib; IFN alpha-2 beta; ipilimumab; melanoma mitomycin C; ocular neoplasm; vemurafenib;

D O I：

10.1586/17469899.2014.921119

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Conjunctival malignant melanoma is a pigmented lesion of the ocular surface. It is an uncommon but potentially devastating tumor that may invade the local tissues of the eye, spread systemically through lymphatic drainage and hematogenous spread, and recur in spite of treatment. Despite its severity, the rarity of available cases has limited the evidence for diagnosis and management. This review will provide an overview of the epidemiology, risk factors, presentation, diagnosis, management, prognosis, staging, and surveillance of conjunctival melanoma, with an emphasis on recent advances in biological therapies to treat this disease.

引用

页码：185 / 204

页数：20

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