NEW INSIGHTS INTO ATHEROSCLEROSIS FROM STUDIES WITH MOUSE MODELS

被引：32
作者：
SHIH, DM
WELCH, C
LUSIS, AJ
机构：
[1] Department of Medicine, 47-123 Center for the Health Sciences, University of California, Los Angeles
来源：
MOLECULAR MEDICINE TODAY | 1995年 / 1卷 / 08期
关键词：
D O I：
10.1016/S1357-4310(95)93834-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Atherosclerosis is a disease of the large arteries that is the cause of heart disease and stroke. It is a highly complex disorder with multiple genetic and environmental influences. The mouse model has proved very useful for studying atherosclerosis because genetic analysis and planned genetic modification are feasible in this organism. In this brief review, some recent findings are summarized and future prospects using mouse models to study atherosclerosis-related traits are discussed.
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页码：364 / 372
页数：9
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