THE HUMAN D11S554 LOCUS - 4 DISTINCT FAMILIES OF REPEAT PATTERN ALLELES AT ONE LOCUS

被引：27

作者：

ADAMS, M ^{[1
]}

URQUHART, A ^{[1
]}

KIMPTON, C ^{[1
]}

GILL, P ^{[1
]}

机构：

[1] FORENS SCI SERV INC,CENT RES & SUPPORT ESTAB,ALDERMASTON RG7 4PN,BERKS,ENGLAND

来源：

HUMAN MOLECULAR GENETICS | 1993年 / 2卷 / 09期

关键词：

D O I：

10.1093/hmg/2.9.1373

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have sequenced amplified products of 44 short tandem repeat alleles at the human D11S554 locus. The sequences revealed four distinct, but related, families of consensus repeat patterns. Six alleles deviated from the consensus patterns. Alleles differed in size by as little as one base pair, and precise sizing is required for analysis of alleles at this highly polymorphic locus. The evolution of alleles at the D11S554 locus and related short tandem repeat loci is discussed.

引用

页码：1373 / 1376

页数：4

共 14 条

[1]

BOSMA PJ, 1988, J BIOL CHEM, V263, P9129

[2] IDENTIFICATION OF SEQUENCE ELEMENTS CONTRIBUTING TO THE INTRINSIC CURVATURE OF THE MOUSE SATELLITE DNA REPEAT [J].

CARRERA, P ;

MARTINEZBALBAS, MA ;

PORTUGAL, J ;

AZORIN, F .

NUCLEIC ACIDS RESEARCH, 1991, 19 (20) :5639-5644

[3] THE HUMAN GROWTH-HORMONE LOCUS - NUCLEOTIDE-SEQUENCE, BIOLOGY, AND EVOLUTION [J].

CHEN, EY ;

LIAO, YC ;

SMITH, DH ;

BARRERASALDANA, HA ;

GELINAS, RE ;

SEEBURG, PH .

GENOMICS, 1989, 4 (04) :479-497

[4] NOVEL NON-TEMPLATED NUCLEOTIDE ADDITION-REACTIONS CATALYZED BY PROCARYOTIC AND EUKARYOTIC DNA-POLYMERASES [J].

CLARK, JM .

NUCLEIC ACIDS RESEARCH, 1988, 16 (20) :9677-9686

[5] HUMAN RIBOSOMAL DNA - CONSERVED SEQUENCE ELEMENTS IN A 4.3-KB REGION DOWNSTREAM FROM THE TRANSCRIPTION UNIT [J].

DICKSON, KR ;

BRAATEN, DC ;

SCHLESSINGER, D .

GENE, 1989, 84 (01) :197-200

[6] THE POLYDEOXYADENYLATE TRACT OF ALU REPETITIVE ELEMENTS IS POLYMORPHIC IN THE HUMAN GENOME [J].

ECONOMOU, EP ;

BERGEN, AW ;

WARREN, AC ;

ANTONARAKIS, SE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (08) :2951-2954

[7] THE 3' ENDS OF ALU REPEATS ARE HIGHLY POLYMORPHIC [J].

EPSTEIN, N ;

NAHOR, O ;

SILVER, J .

NUCLEIC ACIDS RESEARCH, 1990, 18 (15) :4634-4634

[8]

GILL P, 1990, HUM GENET, V85, P75

[9] INSERTION AND OR DELETION OF MANY REPEATED DNA-SEQUENCES IN HUMAN AND HIGHER APE EVOLUTION [J].

HWU, HR ;

ROBERTS, JW ;

DAVIDSON, EH ;

BRITTEN, RJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (11) :3875-3879

[10]

KIMPTON CP, 1993, IN PRESS PCR METHODS

← 1 2 →