THE LACZ TRANSGENE IN MUTA(TM)MOUSE MAPS TO CHROMOSOME-3

被引：16
作者：
SWIGER, RR
MYHR, B
TUCKER, JD
机构：
[1] LAWRENCE LIVERMORE NATL LAB,BIOL & BIOTECHNOL RES PROGRAM,LIVERMORE,CA 94551
[2] HAZLETON WASHINGTON INC,VIENNA,VA 22182
来源：
MUTATION RESEARCH LETTERS | 1994年 / 325卷 / 04期
关键词：
MAPPING; FLUORESCENCE IN SITU HYBRIDIZATION; TRANSGENICS; LACZ; MUTA(TM)MOUSE;
D O I：
10.1016/0165-7992(94)90077-9
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Transgenic mouse models are being used with increasing frequency for mutational and toxicological studies. One such system, MutaMouse, contains a stably integrated lambda-gt10LacZ shuttle vector in the mouse genome. We describe the use of dual color fluorescence in situ hybridization (FISH) with Mus musculus whole chromosome paints and lambda DNA to map the integration site of the lambda transgene to banc C on mouse chromosome 3.
引用
收藏
页码：145 / 148
页数：4
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