SYNTHESIS AND CHARACTERIZATION OF DEXTRAN METHACRYLATES

被引：4

作者：

Donchak, Volodymyr ^{[1
]}

Yuryev, Ruslan ^{[1
]}

Harhay, Khrystyna ^{[1
]}

Voronov, Stanislav ^{[1
]}

机构：

[1] Lviv Polytech Natl Univ, 12 S Bandery Str, UA-79013 Lvov, Ukraine

来源：

CHEMISTRY & CHEMICAL TECHNOLOGY | 2014年 / 8卷 / 03期

关键词：

dextran; methacrylate; macromonomer; biomaterials; hydrogel;

D O I：

10.23939/chcht08.03.303

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Dextran methacrylates were received by acylation of dextran with methacryloilchloride in the presence of tertiary amines in the DMF/LiCl solution. Degree of substitution (DS) of synthesized derivatives reached 1.8 methacrylic residues per glucopyranoside unit of dextran macromolecule. Dextran methacrylates, obtained in the presence of triethylamine, with DS over 0.5 were insoluble in water. Derivatives synthesized in the presence of pyridine were separated in the form of a stable water soluble complex with pyridine chloride. These complexes maintain their water solubility up to DS = 1.8. The structurization of synthesized dextran methacrylates in water solutions initiated by redox system (NH4)(2)S2O8-Et3N yields active hydrogels, containing residual double bonds.

引用

页码：303 / 307

页数：5

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