MOLECULAR REMISSION AFTER ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR CHRONIC LYMPHOCYTIC-LEUKEMIA

被引：0
|
作者：
SADOUN, A
PATRI, S
DELWAIL, V
CHOMEL, JC
COGNE, M
BRIZARD, A
KITZIS, A
GUILHOT, F
机构：
[1] HOP JEAN BERNARD,DEPT HEMATOL & ONCOL MED,F-86021 POITIERS,FRANCE
[2] HOP JEAN BERNARD,BIOL CELLULAIRE & MOLEC LAB,F-86021 POITIERS,FRANCE
[3] HOP JEAN BERNARD,IMMUNOL MOLEC LAB,F-86021 POITIERS,FRANCE
来源：
BONE MARROW TRANSPLANTATION | 1994年 / 13卷 / 02期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
A 51-year-old man with previously treated CLL received an allogeneic sex mismatched BMT after total body irradiation and high dose chemotherapy. Residual disease was studied at phenotypic and molecular levels including Y chromosome DNA amplification by PCR assay. The patient was clinically disease-free 20 months after BMT with disappearance of the leukemic clone assessed by the most sensitive methods of detection. Long-term follow-up is necessary to ascertain the relevance of Y DNA amplification in predicting outcome in this patient.
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页码：217 / 219
页数：3
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