EFFECTIVE AND FIBRIN-SPECIFIC CLOT LYSIS BY A ZYMOGEN PRECURSOR FORM OF UROKINASE (PRO-UROKINASE) - A STUDY INVITRO AND IN 2 ANIMAL SPECIES

被引：317
作者：
GUREWICH, V [1 ]
PANNELL, R [1 ]
LOUIE, S [1 ]
KELLEY, P [1 ]
SUDDITH, RL [1 ]
GREENLEE, R [1 ]
机构：
[1] COLLABORAT RES INC,LEXINGTON,MA 02173
来源：
JOURNAL OF CLINICAL INVESTIGATION | 1984年 / 73卷 / 06期
关键词：
D O I：
10.1172/JCI111381
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：1731 / 1739
页数：9
相关论文
共 25 条
[1]   INCREASED PLASMINOGEN ACTIVATOR (UROKINASE) IN TISSUE-CULTURE AFTER FIBRIN DEPOSITION [J].
BERNIK, MB .
JOURNAL OF CLINICAL INVESTIGATION, 1973, 52 (04) :823-834
[2]  
BRAKMAN P, 1967, FIBRINOLYSIS STANDAR, P1
[3]   IDENTIFICATION AND SOME PROPERTIES OF A NEW FAST-REACTING PLASMIN INHIBITOR IN HUMAN-PLASMA [J].
COLLEN, D .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1976, 69 (01) :209-216
[4]   THROMBOLYSIS WITH HUMAN EXTRINSIC (TISSUE-TYPE) PLASMINOGEN-ACTIVATOR IN RABBITS WITH EXPERIMENTAL JUGULAR VEIN-THROMBOSIS - EFFECT OF MOLECULAR-FORM AND DOSE OF ACTIVATOR, AGE OF THE THROMBUS, AND ROUTE OF ADMINISTRATION [J].
COLLEN, D ;
STASSEN, JM ;
VERSTRAETE, M .
JOURNAL OF CLINICAL INVESTIGATION, 1983, 71 (02) :368-376
[5]   PLASMINOGEN - PURIFICATION FROM HUMAN PLASMA BY AFFINITY CHROMATOGRAPHY [J].
DEUTSCH, DG ;
MERTZ, ET .
SCIENCE, 1970, 170 (3962) :1095-+
[6]  
GUREWICH V, 1983, THROMB HAEMOSTASIS, V50, P1222
[7]  
HUSAIN SS, 1981, THROMB HAEMOSTASIS, V46, P11
[8]   RAPID PURIFICATION OF A HIGH-AFFINITY PLASMINOGEN-ACTIVATOR FROM HUMAN-BLOOD PLASMA BY SPECIFIC ADSORPTION ON FIBRIN-CELITE [J].
HUSAIN, SS ;
LIPINSKI, B ;
GUREWICH, V .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (07) :4265-4269
[9]   PURIFICATION AND PARTIAL CHARACTERIZATION OF A SINGLE-CHAIN HIGH-MOLECULAR-WEIGHT FORM OF UROKINASE FROM HUMAN-URINE [J].
HUSAIN, SS ;
GUREWICH, V ;
LIPINSKI, B .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 220 (01) :31-38
[10]  
KESSLER SW, 1976, J IMMUNOL, V117, P1482
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