ENDOTHELIAL-CELL BINDING OF NAP-1/IL-8 - ROLE IN NEUTROPHIL EMIGRATION

被引：435
作者：
ROT, A
机构：
[1] Antal Rot is ahe Sandoz Forschungsintitut, A-1235 Vienna
来源：
IMMUNOLOGY TODAY | 1992年 / 13卷 / 08期
关键词：
D O I：
10.1016/0167-5699(92)90039-A
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
In this article Antal Rot calls into question the generally accepted notion that gradients of soluble chemotactic factors are responsible for leukocyte emigration from the circulation into sites of inflammation. He presents an alternative model in which chemoattractants bound to the surface of endothelial cells promote neutrophil adhesion and emigration, while soluble blood-borne attractants inhibit adhesion and emigration.
引用
收藏
页码：291 / 294
页数：4
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