LONG-TERM POTENTIATION IN THE PREFRONTAL CORTEX FOLLOWING STIMULATION OF THE HIPPOCAMPAL CA1/SUBICULAR REGION

被引：202

作者：

LAROCHE, S ^{[1
]}

JAY, TM ^{[1
]}

THIERRY, AM ^{[1
]}

机构：

[1] COLL FRANCE,CHAIRE NEUROPHARMACOL,F-75231 PARIS 05,FRANCE

来源：

NEUROSCIENCE LETTERS | 1990年 / 114卷 / 02期

关键词：

Field potential; Hippocampus CA1; Long-term potentiation (LTP); Prefrontal cortex; Subiculum; Unit response;

D O I：

10.1016/0304-3940(90)90069-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have examined single cell activity and field potentials in the prelimbic area of the prefrontal cortex of the rat to electrical stimulation of the CA1/subicular region of the temporal hippocampus. Excitatory unit responses were found in 50 out of 120 neurons recorded in the prelimbic area. Paired-pulse facilitation was found for both single cell responses and field potentials. High-frequency, tetanic stimulation of the temporal hippocampus produced a significant and persistent potentiation of prelimbic field potentials. The evidence suggests that the direct pathway from the temporal hippocampus to the prelimbic area of the prefrontal cortex in the rat is excitatory and can undergo long-term potentiation (LTP). © 1990.

引用

页码：184 / 190

页数：7

共 27 条

[1] SPECIFIC LONG-LASTING POTENTIATION OF SYNAPTIC TRANSMISSION IN HIPPOCAMPAL SLICES [J].

ANDERSEN, P ;

SUNDBERG, SH ;

SVEEN, O ;

WIGSTROM, H .

NATURE, 1977, 266 (5604) :736-737

[2] LONG-TERM POTENTIATION AND NMDA RECEPTORS IN RAT VISUAL-CORTEX [J].

ARTOLA, A ;

SINGER, W .

NATURE, 1987, 330 (6149) :649-652

[3]

BINDMAN LJ, 1987, J PHYSIOL-LONDON, V386, pP90

[4] LONG-LASTING POTENTIATION OF SYNAPTIC TRANSMISSION IN DENTATE AREA OF ANESTHETIZED RABBIT FOLLOWING STIMULATION OF PERFORANT PATH [J].

BLISS, TVP ;

LOMO, T .

JOURNAL OF PHYSIOLOGY-LONDON, 1973, 232 (02) :331-356

[5]

Bloch V, 1984, NEUROBIOLOGY LEARNIN, P249

[6] EXCITATORY AMINO-ACIDS IN SYNAPTIC TRANSMISSION IN THE SCHAFFER COLLATERAL COMMISSURAL PATHWAY OF THE RAT HIPPOCAMPUS [J].

COLLINGRIDGE, GL ;

KEHL, SJ ;

MCLENNAN, H .

JOURNAL OF PHYSIOLOGY-LONDON, 1983, 334 (JAN) :33-46

[7]

FERINO F, 1987, EXP BRAIN RES, V65, P421

[8]

FUSTER JM, 1989, PREFRONTAL CORTEX

[9]

Goldman-Rakic PS, 1987, HDB PHYSL 1, P373, DOI DOI 10.1002/CPHY.CP010509

[10] LONG-TERM POTENTIATION IN THE MOTOR CORTEX [J].

IRIKI, A ;

PAVLIDES, C ;

KELLER, A ;

ASANUMA, H .

SCIENCE, 1989, 245 (4924) :1385-1387

← 1 2 3 →