APORPHINES .50. KINETICS OF SOLVOLYSIS OF N-(2-CHLOROETHYL)NORAPOMORPHINE, AN IRREVERSIBLE DOPAMINE RECEPTOR ANTAGONIST

被引：16
作者：
COHEN, SA
NEUMEYER, JL
机构：
[1] NORTHEASTERN UNIV,MED CHEM SECT,BOSTON,MA 02115
[2] NORTHEASTERN UNIV,INST CHEM ANAL APPLICAT & FOREN SCI,BOSTON,MA 02115
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1983年 / 26卷 / 10期
关键词：
D O I：
10.1021/jm00364a003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1348 / 1353
页数：6
相关论文
共 39 条
[11]   THE EFFECT OF PH ON THE AFFINITIES OF ENZYMES FOR SUBSTRATES AND INHIBITORS [J].
DIXON, M .
BIOCHEMICAL JOURNAL, 1953, 55 (01) :161-170
[12]  
FISHER A, 1982, J PHARMACOL EXP THER, V222, P140
[13]   THE EFFECTS OF (-)N-(CHLOROETHYL)-NORAPOMORPHINE ON [H-3]-LABELED APOMORPHINE BINDING TO STRIATAL DOPAMINE-RECEPTORS [J].
GOOSEY, MW ;
DOGGETT, NS .
BIOCHEMICAL PHARMACOLOGY, 1982, 31 (22) :3693-3694
[14]  
GUAN JH, J MED CHEM
[15]   PHENOXYBENZAMINE DISCRIMINATES MULTIPLE DOPAMINE-RECEPTORS [J].
HAMBLIN, M ;
CREESE, I .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1980, 65 (01) :119-121
[16]  
HAMBLIN MW, 1982, MOL PHARMACOL, V21, P44
[17]   SYNTHESIS AND ADRENORECEPTOR BLOCKING ACTION OF AZIRIDINIUM IONS DERIVED FROM PHENOXYBENZAMINE AND DIBENAMINE [J].
HENKEL, JG ;
PORTOGHESE, PS ;
MILLER, JW ;
LEWIS, P .
JOURNAL OF MEDICINAL CHEMISTRY, 1976, 19 (01) :6-10
[18]  
Kolthoff JM, 1925, BIOCHEM Z, V162, P289
[19]  
KURA G, 1981, J CHROMATOGR, V219, P385
[20]   DOPAMINE AUTORECEPTORS DIFFER PHARMACOLOGICALLY FROM POSTSYNAPTIC DOPAMINE-RECEPTORS - EFFECTS OF (-)-N-(2-CHLOROETHYL)-NORAPOMORPHINE [J].
LEHMANN, J ;
LANGER, SZ .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1982, 77 (01) :85-86
1234