APORPHINES .50. KINETICS OF SOLVOLYSIS OF N-(2-CHLOROETHYL)NORAPOMORPHINE, AN IRREVERSIBLE DOPAMINE RECEPTOR ANTAGONIST

被引：16
作者：
COHEN, SA
NEUMEYER, JL
机构：
[1] NORTHEASTERN UNIV,MED CHEM SECT,BOSTON,MA 02115
[2] NORTHEASTERN UNIV,INST CHEM ANAL APPLICAT & FOREN SCI,BOSTON,MA 02115
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1983年 / 26卷 / 10期
关键词：
D O I：
10.1021/jm00364a003
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：1348 / 1353
页数：6
相关论文
共 39 条
[1]   PHARMACOLOGY OF [APOMORPHINE-H-3 BINDING TO BOVINE BRAIN-TISSUE [J].
ARANA, GW ;
BALDESSARINI, RJ ;
HARDING, M .
BIOCHEMICAL PHARMACOLOGY, 1981, 30 (23) :3171-3179
[2]  
ARANA GW, BIOCH PHARM
[3]   CHLOROETHYLNORAPOMORPHINE, A PROPOSED LONG-ACTING DOPAMINE ANTAGONIST - INTERACTIONS WITH DOPAMINE-RECEPTORS OF MAMMALIAN FOREBRAIN INVITRO [J].
BALDESSARINI, RJ ;
KULA, NS ;
ARANA, GW ;
NEUMEYER, JL ;
LAW, SJ .
EUROPEAN JOURNAL OF PHARMACOLOGY, 1980, 67 (01) :105-110
[4]  
BALDESSARINI RJ, LIFE SCI
[5]  
BARTLETT PD, 1947, J AM CHEM SOC, V69, P2971, DOI 10.1021/ja01204a011
[6]  
Bevington P., 1969, DATA REDUCTION ERROR
[7]  
Cleland W W, 1979, Methods Enzymol, V63, P103
[8]  
COHEN SA, 1983, 185TH NAT M AM CHEM
[9]   ON THE ABILITY OF N-CHLOROETHYL APORPHINE DERIVATIVES TO CAUSE IRREVERSIBLE INHIBITION OF DOPAMINE RECEPTOR MECHANISMS [J].
COSTALL, B ;
FORTUNE, DH ;
GRANCHELLI, FE ;
LAW, SJ ;
NAYLOR, RJ ;
NEUMEYER, JL ;
NOHRIA, V .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1980, 32 (08) :571-576
[10]   (-)N-(CHLOROETHYL)NORAPOMORPHINE INHIBITS STRIATAL DOPAMINE FUNCTION VIA IRREVERSIBLE RECEPTOR-BINDING [J].
COSTALL, B ;
FORTUNE, DH ;
LAW, SJ ;
NAYLOR, RJ ;
NEUMEYER, JL ;
NOHRIA, V .
NATURE, 1980, 285 (5766) :571-573
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