Plasmapheresis Therapy for ANCA Associated Vasculitis with Diffuse Alveolar Hemorrhage: A Case Report and Review of the Literature

被引:0
作者
Yildirim, Fatma [1 ]
Kara, Iskender [2 ]
Tufan, Abdurrahman [3 ]
Turkoglu, Melda [4 ]
Aygencel, Gulbin [4 ]
机构
[1] Gazi Univ, Tip Fak, Gogus Hastaliklari Anabilim Dali, Yogun Bakim Yandal Egitim Programi, Ankara, Turkey
[2] Gazi Univ, Tip Fak, Anesteziyol & Reanimasyon Anabilim Dali, Yogun Bakim Yandal Egitim Programi, Ankara, Turkey
[3] Gazi Univ, Tip Fak, Ic Hastaliklan Anabilim Dali, Romatol Bilim Dali, Ankara, Turkey
[4] Gazi Univ, Tip Fak, Ic Hastaliklari Anabilim Dali, Yogun Bakim Bilim Dali, Ankara, Turkey
来源
GAZI MEDICAL JOURNAL | 2015年 / 26卷 / 04期
关键词
ANCA-associated vasculitis; diffuse alveolar hemorrhage; plasmapheresis therapy;
D O I
10.12996/gmj.2015.59
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diffuse alveolar hemorrhage (DAH) is one of the most serious involvement of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We report a case of a perinuclear-ANCA associated vasculitis with acute renal failure and DAH. The patient received induction immunosuppressive therapy (corticosteroid and cyclophosphamide), but patient's renal function didn't improve and then DAH occured. Plasmapheresis was started as rescue therapy. The DAH didn't resolve at the end of five procedures. Patient died of acute coronary syndrome due to probable coronary vascular involvement.We concluded that plasmapheresis rescue therapy can't get benefit in such a progressive systemic ANCA-associated vasculitis.
引用
收藏
页码:196 / 198
页数:3
相关论文
共 17 条
  • [1] Microscopic polyangiitis presenting as a "Pulmonary-Muscle" syndrome - Is subclinical alveolar hemorrhage the mechanism of pulmonary fibrosis?
    Birnbaum, Julius
    Danoff, Sonye
    Askin, Frederic B.
    Stone, John H.
    [J]. ARTHRITIS AND RHEUMATISM, 2007, 56 (06): : 2065 - 2071
  • [2] Outcome of ANCA-associated renal vasculitis: A 5-year retrospective study
    Booth, AD
    Almond, MK
    Burns, A
    Ellis, P
    Gaskin, G
    Neild, GH
    Plaisance, M
    Pusey, CD
    Jayne, DRW
    [J]. AMERICAN JOURNAL OF KIDNEY DISEASES, 2003, 41 (04) : 776 - 784
  • [3] Plasmapheresis in Diffuse Alveolar Hemorrhage as Perinuclear Antineutrophil Cytoplasmic Antibody-Associated Vasculitis Relapse on Hemodialysis
    Cigarran, Secundino
    Jesus Castro, Maria
    Pousa, Montserrat
    Paredes, Sonia
    Bernardo, Hugo
    Porteiro, Montserrat
    [J]. THERAPEUTIC APHERESIS AND DIALYSIS, 2010, 14 (03) : 368 - 372
  • [4] Pulmonary involvement in microscopic polyangiitis
    Collins, CE
    Quismorio, FP
    [J]. CURRENT OPINION IN PULMONARY MEDICINE, 2005, 11 (05) : 447 - 451
  • [5] Plasmapheresis Rescue Therapy in Progressive Systemic ANCA-Associated Vasculitis: Single-Center Results of Stepwise Escalation of Immunosuppression
    de Joode, Anoek A. E.
    Sanders, Jan S. F.
    Smid, W. Martin
    Stegeman, Coen A.
    [J]. JOURNAL OF CLINICAL APHERESIS, 2014, 29 (05) : 266 - 272
  • [6] A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis
    De Vita, S.
    Quartuccio, L.
    Isola, M.
    Mazzaro, C.
    Scaini, P.
    Lenzi, M.
    Campanini, M.
    Naclerio, C.
    Tavoni, A.
    Pietrogrande, M.
    Ferri, C.
    Mascia, M. T.
    Masolini, P.
    Zabotti, A.
    Maset, M.
    Roccatello, D.
    Zignego, A. L.
    Pioltelli, P.
    Gabrielli, A.
    Filippini, D.
    Perrella, O.
    Migliaresi, S.
    Galli, M.
    Bombardieri, S.
    Monti, G.
    [J]. ARTHRITIS AND RHEUMATISM, 2012, 64 (03): : 843 - 853
  • [7] Pathogenesis of ANCA-associated Vasculitis
    Flint, Julia
    Morgan, Matthew D.
    Savage, Caroline O. S.
    [J]. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2010, 36 (03) : 463 - +
  • [8] PULMONARY HEMORRHAGE COMPLICATING WEGENERS GRANULOMATOSIS AND MICROSCOPIC POLYARTERITIS
    HAWORTH, SJ
    SAVAGE, COS
    CARR, D
    HUGHES, JMB
    REES, AJ
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 1985, 290 (6484): : 1775 - 1778
  • [9] Hogan SL, 1996, J AM SOC NEPHROL, V7, P23
  • [10] Small-vessel vasculitis
    Jennette, JC
    Falk, RJ
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1997, 337 (21) : 1512 - 1523