PREMIER-A Trial of Lifestyle Interventions for Blood Pressure Control: Intervention Design and Rationale

被引:41
作者
Funk, Kristine L. [1 ]
Elmer, Patricia J. [2 ]
Stevens, Victor J. [1 ]
Harsha, David W. [3 ]
Craddick, Shirley R. [1 ]
Lin, Pao-Hwa [4 ]
Young, Deborah Rohm [5 ]
Champagne, Catherine M. [6 ]
Brantley, Phillip J. [7 ,8 ]
McCarron, Phyllis B. [9 ]
Simons-Morton, Denise G. [10 ,11 ]
Appel, Lawrence J. [12 ]
机构
[1] Kaiser Permanente Northwest, Ctr Hlth Res, Portland, OR 97210 USA
[2] Kaiser Permanente Northwest, Ctr Hlth Res, Epidemiol & Nutr, Portland, OR 97210 USA
[3] Pennington Biomed Res Ctr, Body Composit Lab, Baton Rouge, LA 70808 USA
[4] Duke Univ, Sarah Stedman Ctr Nutrit Studies, Med Ctr, Durham, NC USA
[5] Univ Maryland, Dept Kinesiol, College Pk, MD 20742 USA
[6] Pennington Biomed Res Ctr, Dietary Assessment & Food Anal Core Dept, Baton Rouge, LA 70808 USA
[7] Pennington Biomed Res Ctr, Div Educ, Baton Rouge, LA 70808 USA
[8] Pennington Biomed Res Ctr, Behav Med Lab, Baton Rouge, LA 70808 USA
[9] Welch Ctr Prevent Epidemiol & Clin Res, Intervent, Baltimore, MD USA
[10] NIH, Div Epidemiol & Clin Applicat, Bethesda, MD 20892 USA
[11] NIH, Natl Heart Lung & Blood Inst, Bethesda, MD 20892 USA
[12] Johns Hopkins Sch Med, Med Epidemiol & Int Hlth, Baltimore, MD USA
基金
美国国家卫生研究院;
关键词
hypertension; diet; physical activity; behavioral intervention; blood pressure; DASH;
D O I
10.1177/1524839906289035
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Interventions encouraging adoption of healthy diets and increased physical activity are needed to achieve national goals for preventing and treating hypertension, cardiovascular disease, diabetes, and other chronic diseases. PREMIER was a multicenter clinical trial testing the effects of two lifestyle interventions on blood pressure control, compared with advice only. Both interventions implemented established national guidelines for blood pressure control (weight loss, reduced sodium and alcohol intake, and increased physical activity), and one intervention also included the Dietary Approaches to Stop Hypertension (DASH) diet. Both interventions focused on behavioral self-management, motivational enhancement, and personalized feedback. This article describes the design and evaluation approaches for these interventions. Evaluation of multicomponent lifestyle change interventions can help us understand the benefits and difficulties of making multiple lifestyle changes concurrently and the effects such changes can have on blood pressure, particularly in minorities at higher risk for hypertension.
引用
收藏
页码:271 / 280
页数:10
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