ACCUMULATION, EXCRETION AND METABOLISM OF 2,4,6-TRICHLOROPHENYL-4'-NITROPHENYL ETHER BY CARP

被引：5

作者：

TSUDA, T

AOKI, S

KOJIMA, M

HARADA, H

机构：

[1] Shiga Prefectural Institute of Public Health and Environmental Science, Ohtsu, Shiga, 520, 13-45, Gotenhama

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1990年 / 95卷 / 02期

关键词：

D O I：

10.1016/0742-8413(90)90095-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. The bioconcentration factors (BCF) of 2,4,6-trichlorophenyl-4′-nitrophenyl ether (CNP) in carp were 334 ± 13 (mean ± SD, n = 3) for muscle, 542 for liver, 862 for kidney and 547 for gallbladder after 14 days exposure. 2. 2. The excretion rate constants (k) of CNP by carp were 0.12 day-1 for muscle, 0.11 day-1 for liver, 0.28 day-1 for kidney and 0.14 day-1 for gallbladder assuming their processes to be first-order kinetics. 3. 3. 2,4,6-Trichlorophenyl-4′-aminophenyl ether (CNP-amino), 2,4,6-trichlorophenyl-4′-acetamide phenyl ether (CNP-acetamide) and 2,4,6-trichlorophenyl-4′-formamide phenyl ether (CNP-formamide) were detected as metabolites of CNP in muscle and viscera of carp. © 1990.

引用

页码：145 / 150

页数：6

共 17 条

[1]

GOTO S, 1980, SOFT SCI TOKYO

[2] MEASUREMENT OF THE BIOCONCENTRATION FACTORS OF PESTICIDES BY FRESH-WATER FISH AND THEIR CORRELATION WITH PHYSIOCHEMICAL PROPERTIES OR ACUTE TOXICITIES [J].