Gleason score of needle biopsy and radical prostatectomy specimen: what is the correlation?

被引：2

作者：

Qarro, A. ^{[1
]}

Ghoundale, O. ^{[1
]}

Bazine, K. ^{[1
]}

Asseban, M. ^{[1
]}

Najoui, M. ^{[1
]}

Samir, J. ^{[1
]}

Ouhbi, Y. ^{[1
]}

Beddouch, A. ^{[1
]}

Lezrek, M. ^{[1
]}

Alami, M. ^{[1
]}

机构：

[1] Hop Mil Moulay Ismail, Clin Urol, Meknes, Morocco

来源：

AFRICAN JOURNAL OF UROLOGY | 2012年 / 18卷 / 04期

关键词：

` Prostate cancer; Gleason score; Needle biopsy; Radical prostatectomy;

D O I：

10.1016/j.afju.2012.06.006

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction: The Gleason score obtained on biopsies is an essential part of treatment decision making in prostate cancer. This score assesses aggressiveness and progression of the tumor. Objective: To evaluate the correlation between Gleason score at needle biopsy and prostatectomy specimen. Subjects and Methods: We reviewed the records of 30 patients treated for prostate cancer by radical prostatectomy and we evaluated the correlation between Gleason score on biopsy and prostatectomy specimen. Other parameters evaluated were age and PSA. Results: The concordance of Gleason score was 58.82%, upgraded in 35, 29% and downgraded in only 6%. The kappa coefficient was moderate = 0,329. Regarding groups of differentiation, this correlation was 50% in the well differentiated group (Gleason score 2 to 4) and 100% in moderately differentiated group (Gleason score 5 to 7). No patient was classified as poorly differentiated (Gleason score 8 to 10). Conclusion: Gleason score of biopsies may influence treatment and prognosis of localized prostate cancer. It is important to keep in mind that it does not always reflect the true Gleason score, especially in well differentiated cases. (C) 2012 Production and hosting by Elsevier B.V. on behalf of Pan African Urological Surgeons' Association.

引用

页码：183 / 188

页数：6

共 38 条

[1] HETEROGENEITY OF PROSTATE-CANCER IN RADICAL PROSTATECTOMY SPECIMENS [J].