A CATALYTIC ROLE OF CU(II) FOR CONJUGATE ADDITION OF GRIGNARD-REAGENTS - A COMPLETELY DIFFERENT BEHAVIOR FROM ORGANOCUPRATES

被引：20

作者：

AOKI, Y ^{[1
]}

KUWAJIMA, I ^{[1
]}

机构：

[1] TOKYO INST TECHNOL,DEPT CHEM,MEGURO KU,TOKYO 152,JAPAN

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 51期

关键词：

D O I：

10.1016/S0040-4039(00)88514-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Different from lithium dialkylcuprates, Cu(II) catalyzed conjugate addition of Grignard reagents to allylic esters of alpha,beta-unsaturated carboxylates has been effected in the presence of TMS-Cl, and the resulting allyl silyl keteneacetals further undergo rearrangement to afford 2-alkyl 3-alkyl carboxylic acids in good yields.

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页码：7457 / 7460

页数：4

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