POSTNEUROLEPTIC LARYNGEAL DYSKINESIAS - A CAUSE OF UPPER AIRWAY OBSTRUCTIVE SYNDROME IMPROVED BY LOCAL INJECTIONS OF BOTULINUM TOXIN

被引:16
作者
FEVE, A [1 ]
ANGELARD, B [1 ]
FENELON, G [1 ]
LOGAK, M [1 ]
GUILLARD, A [1 ]
SAINTGUILY, JL [1 ]
机构
[1] HOP TENON,SERV OTORHINOLARYNGOL,F-75970 PARIS 20,FRANCE
关键词
UPPER AIRWAY OBSTRUCTION; TARDIVE DYSKINESIA; NEUROLEPTIC; BOTULINUM TOXIN; LARYNGEAL SPASM;
D O I
10.1002/mds.870080220
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
We report a case of laryngeal dyskinesia resulting in severe rest and exercise dyspnea. A 51-year-old man treated for 2 years with flupentixol, an incisive neuroleptic, developed severe dyspnea due to intermittent, rhythmic, and dystonic movements of the vocal cords and upper airway. Local injections of botulinum toxin resulted in spectacular regression of laryngeal spasms and major improvement in breathing. This case emphasizes the risk of upper respiratory dyskinesias associated with neuroleptic treatment and shows the feasibility of a new local treatment in this life-threatening disorder.
引用
收藏
页码:217 / 219
页数:3
相关论文
共 16 条
[11]  
PLACHTA A, 1965, ARCH GEN PSYCHIAT, V12, P152
[12]  
Samie M R, 1987, Mov Disord, V2, P125, DOI 10.1002/mds.870020207
[13]  
Tardive dyskinesia: summary of a task force report of the American psychiatric association, 1980, AM J PSYCHIAT, V137, P1163
[14]  
TURNER A, 1925, BRAIN, V48, P14
[15]   INVOLVEMENT OF UPPER-AIRWAY MUSCLES IN EXTRAPYRAMIDAL DISORDERS - A CAUSE OF AIR-FLOW LIMITATION [J].
VINCKEN, WG ;
GAUTHIER, SG ;
DOLLFUSS, RE ;
HANSON, RE ;
DARAUAY, CM ;
COSIO, MG .
NEW ENGLAND JOURNAL OF MEDICINE, 1984, 311 (07) :438-442
[16]   RESPIRATORY DYSKINESIAS - EXTRAPYRAMIDAL DYSFUNCTION AND DYSPNEA [J].
WEINER, WJ ;
GOETZ, CG ;
NAUSIEDA, PA ;
KLAWANS, HL .
ANNALS OF INTERNAL MEDICINE, 1978, 88 (03) :327-331