IMMUNOCONJUGATES CONTAINING RICIN-A CHAIN AND EITHER HUMAN ANTI-GP41 OR CD4 KILL H9 CELLS INFECTED WITH DIFFERENT ISOLATES OF HIV, BUT DO NOT INHIBIT NORMAL T-CELL OR B-CELL FUNCTION

被引：0
作者：
TILL, MA
GHETIE, V
MAY, RD
AUERBACH, PC
ZOLLAPAZNER, S
GORNY, MK
GREGORY, T
UHR, JW
VITETTA, ES
机构：
[1] UNIV TEXAS,SW MED CTR,DEPT MICROBIOL,5323 HARRY HINES BLVD,DALLAS,TX 75235
[2] VET ADM MED CTR,NEW YORK,NY 10010
[3] GENENTECH INC,DEPT PROC SCI,SAN FRANCISCO,CA 94080
[4] NYU MED CTR,DEPT PATHOL,NEW YORK,NY 10016
来源：
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES AND HUMAN RETROVIROLOGY | 1990年 / 3卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页码：609 / 614
页数：6
相关论文
共 25 条
[1]   GENOMIC HETEROGENEITY OF AIDS RETROVIRAL ISOLATES FROM NORTH-AMERICA AND ZAIRE [J].
BENN, S ;
RUTLEDGE, R ;
FOLKS, T ;
GOLD, J ;
BAKER, L ;
MCCORMICK, J ;
FEORINO, P ;
PIOT, P ;
QUINN, T ;
MARTIN, M .
SCIENCE, 1985, 230 (4728) :949-951
[2]  
Biddison W E, 1983, Diagn Immunol, V1, P112
[3]   SELECTIVE KILLING OF HIV-INFECTED CELLS BY RECOMBINANT HUMAN CD4-PSEUDOMONAS EXOTOXIN HYBRID PROTEIN [J].
CHAUDHARY, VK ;
MIZUKAMI, T ;
FUERST, TR ;
FITZGERALD, DJ ;
MOSS, B ;
PASTAN, I ;
BERGER, EA .
NATURE, 1988, 335 (6188) :369-372
[4]   FUNCTIONAL INTERACTION BETWEEN HUMAN T-CELL PROTEIN CD4 AND THE MAJOR HISTOCOMPATIBILITY COMPLEX HLA-DR ANTIGEN [J].
GAY, D ;
MADDON, P ;
SEKALY, R ;
TALLE, MA ;
GODFREY, M ;
LONG, E ;
GOLDSTEIN, G ;
CHESS, L ;
AXEL, R ;
KAPPLER, J ;
MARRACK, P .
NATURE, 1987, 328 (6131) :626-629
[5]  
GHETIE V, IN PRESS BIOCONJUGAT
[6]   COMMON EPITOPE IN HUMAN IMMUNODEFICIENCY VIRUS (HIV) I-GP41 AND HLA CLASS-II ELICITS IMMUNOSUPPRESSIVE AUTOANTIBODIES CAPABLE OF CONTRIBUTING TO IMMUNE DYSFUNCTION IN HIV I-INFECTED INDIVIDUALS [J].
GOLDING, H ;
SHEARER, GM ;
HILLMAN, K ;
LUCAS, P ;
MANISCHEWITZ, J ;
ZAJAC, RA ;
CLERICI, M ;
GRESS, RE ;
BOSWELL, RN ;
GOLDING, B .
JOURNAL OF CLINICAL INVESTIGATION, 1989, 83 (04) :1430-1435
[7]   IDENTIFICATION OF HOMOLOGOUS REGIONS IN HUMAN IMMUNODEFICIENCY VIRUS-I GP41 AND HUMAN MHC CLASS-II BETA-1 DOMAIN .1. MONOCLONAL-ANTIBODIES AGAINST THE GP41-DERIVED PEPTIDE AND PATIENTS SERA REACT WITH NATIVE HLA CLASS-II ANTIGENS, SUGGESTING A ROLE FOR AUTOIMMUNITY IN THE PATHOGENESIS OF ACQUIRED IMMUNE-DEFICIENCY SYNDROME4 [J].
GOLDING, H ;
ROBEY, FA ;
GATES, FT ;
LINDER, W ;
BEINING, PR ;
HOFFMAN, T ;
GOLDING, B .
JOURNAL OF EXPERIMENTAL MEDICINE, 1988, 167 (03) :914-923
[8]   GENERATION OF HUMAN MONOCLONAL-ANTIBODIES TO HUMAN IMMUNODEFICIENCY VIRUS [J].
GORNY, MK ;
GIANAKAKOS, V ;
SHARPE, S ;
ZOLLAPAZNER, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (05) :1624-1628
[9]  
JELINEK DF, 1985, J IMMUNOL, V134, P1690
[10]   SELECTIVE KILLING OF NORMAL AND NEOPLASTIC HUMAN B-CELLS WITH ANTI-CD19-RICIN AND ANTI-CD22-RICIN A-CHAIN IMMUNOTOXINS [J].
MAY, RD ;
VITETTA, ES ;
MOLDENHAUER, G ;
DORKEN, B .
CANCER DRUG DELIVERY, 1986, 3 (04) :261-272
123