Use of Molecular Markers for Cytologically Indeterminate Thyroid Nodules to Optimize Surgical Management

被引：0
|
作者：
Yip, Linwah [1 ]
机构：
[1] Univ Pittsburgh, Dept Surg, Div Endocrine Surg & Surg Oncol, Suite 101,3471 Fifth Ave, Pittsburgh, PA 15213 USA
来源：
CURRENT SURGERY REPORTS | 2014年 / 2卷 / 01期
关键词：
Thyroid nodule; Thyroid cancer; Thyroidectomy; Molecular markers; Mutation testing; Indeterminate biopsy; Surgical management; MicroRNA; Rearrangements;
D O I：
10.1007/s40137-013-0035-9
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The management of thyroid nodules with indeterminate cytology has traditionally been diagnostic thyroidectomy. However most nodules are benign, and for nodules that demonstrate histologic malignancy, two-stage thyroidectomy may be necessary. Molecular markers have emerged as an adjunct to preoperative FNAB cytology evaluation that can improve diagnostic accuracy. In this review, we discuss the latest methodologies and review diagnostic performance parameters of recent molecular marker techniques.
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页数：7
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