RECENT ADVANCES IN THE MOLECULAR-BIOLOGY OF HEPATITIS-B VIRUS

被引：0
|
作者：
BRENARD, R
机构：
来源：
ACTA GASTRO-ENTEROLOGICA BELGICA | 1993年 / 56卷 / 01期
关键词：
HBS AG; HBE AG; HBV VARIANT; HBV REPLICATION; CHRONIC HEPATITIS-B; FULMINANT HEPATITIS-B;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Recent advances in the molecular biology of hepatitis B virus. Recent advances in molecular biology had led to a better understanding of the pathology of hepatitis B virus. The polymerase chain reaction technique has shown that the genome of hepatitis B virus is highly variable. Mutations in the pre-core region are associated with HBe Ag negative chronic hepatitis and fulminant hepatitis B moreover, HBV vaccine induce mutations within the S gene and escape mutant of hepatitis B virus in immunized patients. The aim of this paper is to assess the clinical, serological and therapeutic features of hepatitis B variants.
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页码：18 / 23
页数：6
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