OPTIMAL DOSE OF LIGNOCAINE FOR PREVENTING PAIN ON INJECTION OF PROPOFOL

被引:54
作者
GEHAN, G [1 ]
KAROUBI, P [1 ]
QUINET, F [1 ]
LEROY, A [1 ]
RATHAT, C [1 ]
POURRIAT, JL [1 ]
机构
[1] UNIV PARIS 13,CHU AVICENNE JEAN VERDIER,DEPT ANESTHESIE REANIMAT,F-93000 BOBIGNY,FRANCE
关键词
ANESTHETICS; INTRAVENOUS; PROPOFOL; COMPLICATIONS; PAIN;
D O I
10.1093/bja/66.3.324
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The purpose of this study was to define the optimum dose of lignocaine required to reduce pain on injection of propofol. We conducted a prospective, randomized, double-blind trial on 310 patients undergoing anaesthesia. Patients were allocated to four groups according to the lignocaine dosage: group A (control), no lignocaine; group B, lignocaine 0.1 mg kg-1; group C, lignocaine 0.2 mg kg-1; group D, lignocaine 0.4 mg kg-1. Our results showed that a dose of lignocaine 0.1 mg kg-1 significantly reduced the incidence of pain and that there was no improvement when the dose was increased.
引用
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页码:324 / 326
页数:3
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