CARCINOSARCOMA OF THE URINARY-BLADDER - A DISTINCT VARIANT CHARACTERIZED BY SMALL-CELL UNDIFFERENTIATED CARCINOMA WITH NEUROENDOCRINE FEATURES

被引：16

作者：

MAZZUCCHELLI, L ^{[1
]}

KRAFT, R ^{[1
]}

GERBER, H ^{[1
]}

EGGER, C ^{[1
]}

STUDER, UE ^{[1
]}

ZIMMERMANN, A ^{[1
]}

机构：

[1] UNIV BERN,DEPT UROL,CH-3010 BERN,SWITZERLAND

来源：

VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY | 1992年 / 421卷 / 06期

关键词：

URINARY BLADDER; CARCINOSARCOMA; SMALL CELL UNDIFFERENTIATED CARCINOMA; NEUROENDOCRINE DIFFERENTIATION; IMMUNOHISTOCHEMISTRY;

D O I：

10.1007/BF01606876

中图分类号：

R602 [外科病理学、解剖学]; R32 [人体形态学];

学科分类号：

100101 ;

摘要：

The clinicopathological features of two carcinosarcomas of the urinary bladder are reported. The tumours occurred in a 64- and a 66-year-old patient presenting with haematuria and both were polypoid. The epithelial component was consistent with small cell undifferentiated carcinoma with neuroendocrine differentiation, whereas the sarcomatous component did not display specific features. The carcinomatous component showed immunohistochemical reactivity for different epithelial markers as well as for chromogranin and neuron specific enolase. Conversely, the sarcomatous cells stained strongly for vimentin and in one case for muscle actin and smooth muscle actin. The differential diagnosis of biphasic tumours of the bladder is discussed and the literature reviewed.

引用

收藏

页码：477 / 483

页数：7

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