AN EXPERIMENTAL APPROACH TO TESTING MODULAR EVOLUTION - DIRECTED REPLACEMENT OF ALPHA-HELICES IN A BACTERIAL PROTEIN

被引：16
作者：
DUBOSE, RF
HARTL, DL
机构：
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 24期
关键词：
D O I：
10.1073/pnas.86.24.9966
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
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页码：9966 / 9970
页数：5
相关论文
共 28 条
[1]  
BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3
[2]   THE MOLECULAR EVOLUTION OF GENES AND PROTEINS - A TALE OF 2 SERINES [J].
BRENNER, S .
NATURE, 1988, 334 (6182) :528-530
[3]   USE OF SITE-DIRECTED MUTAGENESIS TO ELUCIDATE THE ROLE OF ARGININE-166 IN THE CATALYTIC MECHANISM OF ALKALINE-PHOSPHATASE [J].
BUTLERRANSOHOFF, JE ;
KENDALL, DA ;
KAISER, ET .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (12) :4276-4278
[4]   FUNCTION OF ARGININE-166 IN THE ACTIVE-SITE OF ESCHERICHIA-COLI ALKALINE-PHOSPHATASE [J].
CHAIDAROGLOU, A ;
BREZINSKI, DJ ;
MIDDLETON, SA ;
KANTROWITZ, ER .
BIOCHEMISTRY, 1988, 27 (22) :8338-8343
[5]   SPECULATIONS ON THE EARLY COURSE OF EVOLUTION [J].
DARNELL, JE ;
DOOLITTLE, WF .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (05) :1271-1275
[6]  
DUBOSE R F, 1987, Genetics, V116, pS43
[7]   GENETIC EXCHANGE AMONG NATURAL ISOLATES OF BACTERIA - RECOMBINATION WITHIN THE PHOA GENE OF ESCHERICHIA-COLI [J].
DUBOSE, RF ;
DYKHUIZEN, DE ;
HARTL, DL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (18) :7036-7040
[8]  
DYKHUIZEN DE, 1985, EVOLUTION, V39, P1, DOI 10.1111/j.1558-5646.1985.tb04075.x
[9]   MOLECULAR EVOLUTION OF CYTOCHROME-C IN EUKARYOTES [J].
FITCH, WM .
JOURNAL OF MOLECULAR EVOLUTION, 1976, 8 (01) :13-40
[10]   GENES-IN-PIECES REVISITED [J].
GILBERT, W .
SCIENCE, 1985, 228 (4701) :823-824
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