Rev-erb beta 2, a novel isoform of the Rev-erb family of orphan nuclear receptors

被引：0

作者：

Giambiagi, N ^{[1
]}

Cassia, R ^{[1
]}

Petropoulos, I ^{[1
]}

Part, D ^{[1
]}

Cereghini, S ^{[1
]}

Zakin, MM ^{[1
]}

Ochoa, A ^{[1
]}

机构：

[1] INST PASTEUR,UNIV GENET DIFFERENTIAT,F-75724 PARIS 15,FRANCE

来源：

BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL | 1995年 / 37卷 / 06期

关键词：

hormone nuclear receptors; orphan receptors; Rev-erb family; isoforms;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated a rat complementary DNA clone corresponding to a novel isoform of the hormone nuclear receptor superfamily. This clone encodes a 383 amino acid residue protein designated as Rev-erb beta 2. This protein is identical until residue 382 to the Rev-erb beta 1 protein, which is 195 amino acids longer. Several arguments pointed out that the Rev-erb beta 2 cDNA may originate from the same gene as Rev-erb beta 1 by alternative splicing and using a different polyadenylation site. Our results indicate that Rev-erb beta 2 is a new isoform of the Rev-erb family of orphan nuclear receptors.

引用

页码：1091 / 1102

页数：12

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