PREFABRICATION OF A VASCULARIZED NERVE GRAFT BY VESSEL IMPLANTATION - PRELIMINARY-REPORT OF AN EXPERIMENTAL-MODEL

被引：12

作者：

CAVADAS, PC ^{[1
]}

VERASEMPERE, FJ ^{[1
]}

机构：

[1] HOSP UNIV LA FE,DEPT PLAST SURG,VALENCIA,SPAIN

来源：

MICROSURGERY | 1994年 / 15卷 / 12期

关键词：

D O I：

10.1002/micr.1920151210

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Regeneration through vascularized nerve grafts (VNG) seems to be better than nonvascularized nerve grafts (NVNG), especially in hostile beds. We report on an experimental technique of prefabrication of VNG by direct vessel implantation. An arteriovenous fistula was created in the groin region with autologous vein grafts in the Wistar rat model, and implanted into the sciatic nerve. Five weeks later the sciatic VNG was elevated on the prefabricated pedicle. The flap was free-transferred orthotopically over a silicone sheet to impede plasmatic imbibition. Flap viability at 3 days was complete. India ink injection of the AV fistula resulted in capillary ink filling within the nerve and surrounding tissues. Histologic sections of the flap were examined, revealing its neovascularity. In an ongoing study, the regeneration through this prefabricated VNG is being compared to native VNG. (C) 1994 Wiley-Liss, Inc.

引用

页码：877 / 881

页数：5

共 20 条

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