SEQUENCE OF THE PROMOTER REGION OF THE MOUSE GENE ENCODING ORNITHINE AMINOTRANSFERASE

被引：8
|
作者：
SHULL, JD
ESUMI, N
COLWELL, AS
PENNINGTON, KL
JENDOUBI, M
机构：
[1] UNIV NEBRASKA, MED CTR, DEPT BIOCHEM & MOLEC BIOL, OMAHA, NE 68198 USA
[2] NEI, IMMUNOL LAB, GENET & MOLEC IMMUNOL SECT, BETHESDA, MD 20892 USA
来源：
GENE | 1995年 / 162卷 / 02期
关键词：
GENE STRUCTURE; RECOMBINANT DNA; REGULATORY REGION; HUMAN OAT; RAT OAT; GYRATE ATROPHY; NUCLEOTIDE SEQUENCE;
D O I：
10.1016/0378-1119(95)00309-T
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
We have isolated and sequenced the promoter region of the mouse gene (mOAT) encoding ornithine aminotransferase. A comparison of these mOAT sequences with previously reported sequences for the rat and human genes encoding .OAT, rOAT and hOAT, respectively, revealed a 256-bp region flanking the transcription start point that is highly conserved between the three genes. This region contains sequence motifs resembling binding sites for general transcription factors, as well as other traits-acting regulatory proteins.
引用
收藏
页码：275 / 277
页数：3
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