IMMUNOLOGICAL RESPONSE TO A HEPATITIS-B VACCINE IN ANTI-HBC-POSITIVE HOSPITAL EMPLOYEES WITH NO OTHER HEPATITIS-B VIRUS MARKERS

被引：0
作者：
AJMI, S [1 ]
CHATTI, N [1 ]
BOUGUERRA, M [1 ]
YACOUB, S [1 ]
GHACHEM, L [1 ]
JEMNI, L [1 ]
机构：
[1] CHU F HACHED SOUSSE,SERV HEPATOLGASTRO ENTEROL,4000 SOUSSE,TUNISIA
来源：
SEMAINE DES HOPITAUX | 1993年 / 69卷 / 19期
关键词：
HEPATITIS-B; ANTI-HBC ANTIBODIES; EPIDEMIOLOGY;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Significance of isolated anti-HBc positivity among hospital employees was evaluated by studying the antibody response to a hepatitis B vaccine (r-DNA Hepatitis B vaccine, SKF Laboratories) in 49 subjects. Response was primary in 49 % of subjects, secondary in 16.3 %, and weak or absent in 34.7 %. Secondary reactions were more common among females. These data demonstrate that there is no single interpretation of isolated anti-HBc positivity. Nearly half of the subjects with anti-HBc-antibodies as the only hepatitis B marker may require immunization.
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页码：570 / 572
页数：3
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