REPRODUCTION AND TERATOLOGY STUDIES WITH ONCOLYTIC AGENTS IN RAT AND RABBIT .2. 5-(3,3-DIMETHYL-I-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE (DTIC)

被引：9

作者：

THOMPSON, DJ ^{[1
]}

MOLELLO, JA ^{[1
]}

STREBING, RJ ^{[1
]}

DYKE, IL ^{[1
]}

机构：

[1] DOW CHEM CO,DEPT PATHOL & TOXICOL,INDIANAPOLIS,IN 46268

来源：

TOXICOLOGY AND APPLIED PHARMACOLOGY | 1975年 / 33卷 / 02期

关键词：

D O I：

10.1016/0041-008X(75)90095-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：281 / 290

页数：10

共 11 条

[1]

CHAUBE S, 1973, CANCER RES, V33, P2231

[2]

COSTANZA ME, 1972, CANCER-AM CANCER SOC, V30, P1457, DOI 10.1002/1097-0142(197212)30:6<1457::AID-CNCR2820300607>3.0.CO

[3]

2-5

[4] CLINICAL EVALUATION OF 5-(3,3-DIMETHYL-1-TRIAZENO)IMIDAZOLE-4-CARBOXAMIDE IN MALIGNANT MELANOMA AND OTHER NEOPLASMS - COMPARISON OF TWICE-WEEKLY AND DAILY ADMINISTRATION SCHEDULES [J].

GOTTLIEB, JA ;

SERPICK, AA .

ONCOLOGY, 1971, 25 (03) :225-&

[5]

HANO K, 1965, GANN, V56, P417

[6]

HOFFMAN G, 1968, CANCER CHEMOTH REP 1, V52, P715

[7] ANTITUMOR ACTIVITY OF TRIAZENOIMIDAZOLES [J].

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LASTER, WR ;

MONTGOMERY, JA .

BIOCHEMICAL PHARMACOLOGY, 1962, 11 (JUL) :674-&

[8] SYNTHESES AND BIOLOGICAL ACTIVITY OF 5-AMINOIMIDAZOLES AND 5-TRIAZENOIMIDAZOLES [J].

SHEALY, YF .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1970, 59 (11) :1533-&

[9] METHYLATION OF NUCLEIC ACIDS AND URINARY EXCRETION OF C-14-LABELED 7-METHYLGUANINE BY RATS AND MAN AFTER ADMINISTRATION OF 4(5)-(3,3-DIMETHYL-L-TRIAZENO)-IMIDAZOLE 5(4)-CARBOXOMIDE [J].

SKIBBA, JL ;

BRYAN, GT .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1971, 18 (03) :707-&

[10] REPRODUCTION AND TERATOLOGY STUDIES WITH ONCOLYTIC AGENTS IN RAT AND RABBIT .1. 1,3-BIS(2-CHLOROETHYL)-1-NITROSOUREA (BCNU) [J].

THOMPSON, DJ ;

MOLELLO, JA ;

STREBING, RJ ;

DYKE, IL ;

ROBINSON, VB .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1974, 30 (03) :422-439

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