HUMAN PROTO-ONCOGENE C-MOS MAPS TO 8Q11

被引：61

作者：

CAUBET, JF ^{[1
]}

MATHIEUMAHUL, D ^{[1
]}

BERNHEIM, A ^{[1
]}

LARSEN, CJ ^{[1
]}

BERGER, R ^{[1
]}

机构：

[1] HOP ST LOUIS, UER HEMATOL,ONCOL & IMMUNOHEMATOL LAB,CNRS,LP 101, 2 PL DR FOURNIER, F-75475 PARIS 10, FRANCE

来源：

EMBO JOURNAL | 1985年 / 4卷 / 09期

关键词：

D O I：

10.1002/j.1460-2075.1985.tb03921.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hybridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos have been found in acute leukemia with the chromosomal translocation t(8;21)(q22;q22).

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页码：2245 / 2248

页数：4

相关论文

共 15 条

[1] CHROMOSOME REARRANGEMENTS IN ACQUIRED MALIGNANT DISEASES [J].

BERGER, R ;

BERNHEIM, A ;

DELACHAPELLE, A .

CYTOGENETICS AND CELL GENETICS, 1982, 32 (1-4) :205-207

[2] DIRECT HYBRIDIZATION OF SORTED HUMAN-CHROMOSOMES - LOCALIZATION OF THE Y-CHROMOSOME ON THE FLOW KARYOTYPE [J].

BERNHEIM, A ;

METEZEAU, P ;

GUELLAEN, G ;

FELLOUS, M ;

GOLDBERG, ME ;

BERGER, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (24) :7571-7575

[3]

BERNHEIM A, 1983, HUM GENET, V63, P303

[4] AN IMPROVED METHOD FOR G-BANDING CHROMOSOMES AFTER INSITU HYBRIDIZATION [J].

CANNIZZARO, LA ;

EMANUEL, BS .

CYTOGENETICS AND CELL GENETICS, 1984, 38 (04) :308-309

[5] ISOLATION AND ANALYSIS OF THE 21Q+ CHROMOSOME IN THE ACUTE MYELOGENOUS LEUKEMIA 8-21 TRANSLOCATION - EVIDENCE THAT C-MOS IS NOT TRANSLOCATED [J].

DRABKIN, HA ;

DIAZ, M ;

BRADLEY, CM ;

LEBEAU, MM ;

ROWLEY, JD ;

PATTERSON, D .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (02) :464-468

[6] LOCALIZATION OF SINGLE COPY DNA-SEQUENCES ON G-BANDED HUMAN-CHROMOSOMES BY INSITU HYBRIDIZATION [J].

HARPER, ME ;

SAUNDERS, GF .

CHROMOSOMA, 1981, 83 (03) :431-439

[7]

KUFF EL, 1983, NATURE, V306, P795

[8] CATALOG OF CHROMOSOME-ABERRATIONS IN CANCER [J].

MITELMAN, F .

CYTOGENETICS AND CELL GENETICS, 1983, 36 (1-2) :1-+

[9] 2 HUMAN C-ONC GENES ARE LOCATED ON THE LONG ARM OF CHROMOSOME-8 [J].

NEEL, BG ;

JHANWAR, SC ;

CHAGANTI, RSK ;

HAYWARD, WS .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (24) :7842-7846

[10] PROPERTIES OF A NORMAL MOUSE-CELL DNA-SEQUENCE (SARC) HOMOLOGOUS TO THE SRC SEQUENCE OF MOLONEY SARCOMA-VIRUS [J].

OSKARSSON, M ;

MCCLEMENTS, WL ;

BLAIR, DG ;

MAIZEL, JV ;

VANDEWOUDE, GF .

SCIENCE, 1980, 207 (4436) :1222-1224