Intravitreal bevacizumab for macular edema secondary to branch retinal vein occlusion Original Article

被引:0
作者
Aytug, Banu
Yanyali, Ates [1 ]
Nohutcu, Ahmet Fazil [2 ]
机构
[1] Goz Klin, Haydarpasa Numune Egitim & Arastirma Hastanesi, Istanbul, Turkey
[2] Goz Klin, Klin Sefi Haydarpasa Numune Egitim & Arastirma Ha, Istanbul, Turkey
来源
TURK OFTALMOLOJI DERGISI-TURKISH JOURNAL OF OPHTHALMOLOGY | 2009年 / 39卷 / 02期
关键词
branch retinal vein occlusion; macular edema; optical coherens tomography; intravitreal; bevacizumab;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: To re zunrah injection C C,u Nlacular Edema Secondary In Branch Retinal :kne.s,s and visual Kull lianges alter intravitreal ndary to branch retinal vein occlusion. Method: In Illis retrospe tine study, 15 eves of 15 patients ulltcth I A vastini injection for til xcnlar edema secondary to branch re Eves with br,tinch retin;iI arid pi:.)stimection optical coherens tomography (CT) measures and fovea] thickness were included in die study. All eyes received at kast 3 intravitreal my hev. cizuI fah monthly. Main outcome measure were Early Treatment Diabet Study (El DRS) Fisual acuity and fovea! thickness chanves, and complications, Results: Mean follow-up was 4.8 +/- 1.7 Its. Mean loveal 493.20 +/- 04,77 rum at baseline. 241,38 +/- 16,02 mm to 1 month. 253.60 +/- 109.03 min ai min at 3 months. 276.30 +/- 00.20 rum at tr months. Mean decrease its I dud. tiN - at postirnect nth.; I. 2. 3. and ( rp <0.0I}. Mean ETDRS; se ores iSnclIcni were 55,57 I -1,9d "t at - (i9,47+9,93 i.10/5 r 72.1.31-N,7.4 121)/4(.0 at 2 months, 72,08 +/- 9,56 120/40) at 3 mona,;, and months. change in Ell* S letters from baseline to months I. 2, 3, and r) ware cr(1.1.H I. Vitreous inflammation was 461.tscryt!t1 in one Patient. Conclusion: Inuziviircd1 INyaclzuniah injection for macular edema sect In cx'cl'tl lnl was effective and safe al early period. Further studies. with a *I.T;, to f patients are required.
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页码:121 / 128
页数:8
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共 30 条
  • [1] Changes in retinal neovascularization after pegaptanib (Macugen) therapy in diabetic individuals
    Adamis, AP
    Altaweel, M
    Bressler, NM
    Cunningham, ET
    Davis, MD
    Goldbaum, M
    Gonzales, C
    Guyer, DR
    Katz, B
    Patel, M
    [J]. OPHTHALMOLOGY, 2006, 113 (01) : 23 - 28
  • [2] INCREASED VASCULAR ENDOTHELIAL GROWTH-FACTOR LEVELS IN THE VITREOUS OF EYES WITH PROLIFERATIVE DIABETIC-RETINOPATHY
    ADAMIS, AP
    MILLER, JW
    BERNAL, MT
    DAMICO, DJ
    FOLKMAN, J
    YEO, TK
    YEO, KT
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 1994, 118 (04) : 445 - 450
  • [3] VASCULAR ENDOTHELIAL GROWTH-FACTOR IN OCULAR FLUID OF PATIENTS WITH DIABETIC-RETINOPATHY AND OTHER RETINAL DISORDERS
    AIELLO, LP
    AVERY, RL
    ARRIGG, PG
    KEYT, BA
    JAMPEL, HD
    SHAH, ST
    PASQUALE, LR
    THIEME, H
    IWAMOTO, MA
    PARK, JE
    NGUYEN, HV
    AIELLO, LM
    FERRARA, N
    KING, GL
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (22) : 1480 - 1487
  • [4] [Anonymous], 1986, Arch Ophthalmol, V104, P34
  • [5] [Anonymous], 1984, AM J OPHTHALMOL, V98, P271
  • [6] Intravitreal bevacizumab (Avastin) for neovascular age-related macular degeneration
    Avery, RL
    Pieramici, DJ
    Rabena, MD
    Castellarin, AA
    Nasir, MA
    Giust, MJ
    [J]. OPHTHALMOLOGY, 2006, 113 (03) : 363 - 372
  • [7] Vitreous levels of unbound bevacizumab and unbound vascular endothelial growth factor in two patients
    Beer, Paul M.
    Wong, Susan J.
    Hammad, Amjad M.
    Falk, Naomi S.
    O'Malley, Martin R.
    Khan, Samira
    [J]. RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2006, 26 (08): : 871 - 876
  • [8] Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection
    Beer, PM
    Bakri, SJ
    Singh, RJ
    Liu, WG
    Peters, GB
    Miller, M
    [J]. OPHTHALMOLOGY, 2003, 110 (04) : 681 - 686
  • [9] Boyd SR, 2002, ARCH OPHTHALMOL-CHIC, V120, P1644
  • [10] Cekic O, 2005, RETINA, V7, P852