STRUCTURAL STUDIES OF NEW MACROLIDE ANTIBIOTICS, SHURIMYCIN-A AND SHURIMYCIN-B

被引:17
作者
KUMAZAWA, S [1 ]
ASAMI, Y [1 ]
AWANE, K [1 ]
OHTANI, H [1 ]
FUKUCHI, C [1 ]
MIKAWA, T [1 ]
HAYASE, T [1 ]
机构
[1] MITSUBISHI KASEI CORP,RES CTR,MIDORI KU,YOKOHAMA 227,JAPAN
关键词
D O I
10.7164/antibiotics.47.688
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The structures of new antibiotics, shurimycins A and B produced by Streptomyces hygroscopicus A1491, were elucidated from the physico-chemical properties, 2D NMR techniques and chemical degradation experiments to be 36-membered macrolides related to azalomycins, scopafungin and guanidylfungins. Shurimycins were active against fungi and Gram-positive bacteria.
引用
收藏
页码:688 / 696
页数:9
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