A CASE OF WERNERS-SYNDROME ASSOCIATED WITH SYSTEMIC LUPUS-ERYTHEMATOSUS

被引：4

作者：

KOGURE, A

OHSHIMA, Y

WATANABE, N

OHBA, T

MIYATA, M

OHARA, M

NISHIMAKI, T

KASUKAWA, R

机构：

[1] Department of Internal Medicine II, Fukushima Medical College, Fukushima, 960-12

来源：

CLINICAL RHEUMATOLOGY | 1995年 / 14卷 / 02期

关键词：

WERNERS SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; HLA;

D O I：

10.1007/BF02214944

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The case of a 40-year-old woman with Werner's syndrome associated with systemic lupus erythematosus (SLE) is reported. The patient exhibited short stature, slender extremities, thinned hair, high-pitched voice, cataracts, ulceration of the fingers, and mental retardation. Malar erythema, photosensitivity, and proteinuria had been noted since age 34. The serum contained high titers of antibodies to dsDNA, Sm, nRNP, and SS-A/Ro. The simultaneous presence of Werner's syndrome and SLE could be a coincidental occurrence of the two diseases, although it might be due to an abnormality in replication or degeneration of DNA leading to the development of both diseases.

引用

页码：199 / 203

页数：5

共 14 条

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