A SIMPLE METHOD FOR MEASURING PATIENT ANTI-GLOBULIN RESPONSES AGAINST ISOTYPIC OR IDIOTYPIC DETERMINANTS

被引：47

作者：

COBBOLD, SP ^{[1
]}

REBELLO, PRUB ^{[1
]}

DAVIES, HFS ^{[1
]}

FRIEND, PJ ^{[1
]}

CLARK, MR ^{[1
]}

机构：

[1] NEW ADDENBROOKES HOSP, DEPT SURG, CAMBRIDGE CB2 2QQ, ENGLAND

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1990年 / 127卷 / 01期

基金：

英国医学研究理事会;

关键词：

Anti-globulin; Anti-idiotype; ELISA; Monoclonal antibody; Transplantation;

D O I：

10.1016/0022-1759(90)90335-S

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple inhibition of capture enzyme-linked immunosorbent assay (IOC-ELISA) was developed which permitted the independent measurement of anti-idiotypic and anti-isotypic antiglobulins in serum samples from patients receiving therapeutic monoclonal antibodies. © 1990.

引用

页码：19 / 24

页数：6

共 15 条

[1]

AALBERSE RC, 1983, J IMMUNOL, V130, P722

[2]

FRIEND PJ, 1986, TRANSPLANT P, V18, P1291

[3] RAT-X-RAT HYBRID MYELOMAS AND A MONOCLONAL ANTI-FD PORTION OF MOUSE IGG [J].

GALFRE, G ;

MILSTEIN, C ;

WRIGHT, B .

NATURE, 1979, 277 (5692) :131-133

[4]

GOLDSTEIN G, 1985, NEW ENGL J MED, V313, P337

[5] OKT3 MONOCLONAL-ANTIBODY PLASMA-LEVELS DURING THERAPY AND THE SUBSEQUENT DEVELOPMENT OF HOST ANTIBODIES TO OKT3 [J].

GOLDSTEIN, G ;

FUCCELLO, AJ ;

NORMAN, DJ ;

SHIELD, CF ;

COLVIN, RB ;

COSIMI, AB .

TRANSPLANTATION, 1986, 42 (05) :507-511

[6] ISOLATION OF LOW-FREQUENCY CLASS-SWITCH VARIANTS FROM RAT HYBRID MYELOMAS [J].

HALE, G ;

COBBOLD, SP ;

WALDMANN, H ;

EASTER, G ;

MATEJTSCHUK, P ;

COOMBS, RRA .

JOURNAL OF IMMUNOLOGICAL METHODS, 1987, 103 (01) :59-67

[7]

HALE G, 1985, J IMMUNOL, V134, P3056

[8]

HALE G, 1988, LANCET, V2, P1394

[9]

HALE G, 1983, BLOOD, V62, P873

[10] MONOCLONAL-ANTIBODY THERAPY - ANTIIDIOTYPIC AND NON-ANTI-IDIOTYPIC ANTIBODIES TO OKT3 ARISING DESPITE INTENSE IMMUNOSUPPRESSION [J].

JAFFERS, GJ ;

FULLER, TC ;

COSIMI, AB ;

RUSSELL, PS ;

WINN, HJ ;

COLVIN, RB .

TRANSPLANTATION, 1986, 41 (05) :572-578

← 1 2 →