Kingella kingae spondylodiscitis in young children: toward a new approach for bacteriological investigations? A preliminary report

被引:24
作者
Ceroni, Dimitri [1 ]
Cherkaoui, Abdessalam [2 ]
Kaelin, Andre [1 ]
Schrenzel, Jacques [3 ]
机构
[1] Univ Hosp Geneva, Pediat Orthoped Serv, CH-1211 Geneva 14, Switzerland
[2] Univ Hosp Geneva, Infect Dis Serv, Clin Microbiol Lab, CH-1211 Geneva 14, Switzerland
[3] Univ Hosp Geneva, Clin Epidemiol Serv, CH-1211 Geneva 14, Switzerland
关键词
Kingella kingae; Osteoarticular infection; Spondylodiscitis; Children; qPCR;
D O I
10.1007/s11832-009-0233-2
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
As the result of improved bacteriological techniques, Kingella kingae is a slow-growing Gram-negative coccobacillus that is emerging as an important cause of spondylodiscitis in children younger than 3 years of age. The high pharyngeal carrier rates of this slow-growing Gram-negative coccobacillus combined with the low incidence of identified K. kingae infections is possibly explained by a low virulence of this bacterium. The use of specific real-time polymerase chain reaction (PCR) on blood samples and throat swabs opens new prospects in the bacteriological investigations of young children suspected to have spondylodiscitis, an approach that could prevent, in the future, unnecessary invasive interventions.
引用
收藏
页码:173 / 175
页数:3
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