FRAGILE-X FREQUENCY IN A MENTALLY-RETARDED POPULATION IN BRAZIL

被引：9

作者：

MINGRONINETTO, RC ^{[1
]}

ROSENBERG, C ^{[1
]}

VIANNAMORGANTE, AM ^{[1
]}

PAVANELLO, RDM ^{[1
]}

机构：

[1] UNIV SAO PAULO, DEPT BIOL, CAIXA POSTAL 11461, BR-05499 SAO PAULO, BRAZIL

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1990年 / 35卷 / 01期

关键词：

Martin-Bell syndrome; Mental retardation survey; X-linked mental retardation;

D O I：

10.1002/ajmg.1320350106

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Seventy-five male and 50 female students from 2 special schools for mildly, moderately retarded, or borderline individuals were screened clinically and cytogenetically in order to estimate the contribution of fragile X [fra(X)] syndrome to the cause of mental retardation in Brazil. We found 6 males (8%) from 4 families and 2 unrelated females (4%) with fra(X) chromosomes. One male and one female were isolated cases. The estimated frequency of Martin-Bell [fra(X)] syndrome among mentally impaired individuals in Brazil was similar to that previously reported in other countries.

引用

页码：22 / 27

页数：6

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