EFFECTS OF CHOLINERGIC AGONISTS ON THE DORSAL IMMOBILITY RESPONSE

被引：6
|
作者：
POTTER, TJ [1 ]
COTTRELL, GA [1 ]
VANHARTESVELDT, C [1 ]
机构：
[1] UNIV FLORIDA,DEPT PSYCHOL,GAINESVILLE,FL 32611
来源：
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1990年 / 36卷 / 01期
关键词：
Arecoline; Dorsal immobility response; Physostigmine; Pilocarpine; Rat; Scopolamine;
D O I：
10.1016/0091-3057(90)90128-5
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The effects of pilocarpine, arecoline, and physostigmine on the dorsal immobility response in ovariectomized female rats were tested. The effect of pretreatment with the cholinergic antagonist scopolamine was also tested. Pilocarpine, arecoline, and physostigmine all significantly decreased the duration of the dorsal immobility response in a dose-dependent way. Scopolamine significantly blocked the effect of pilocarpine. Thus, cholinergic agonists attenuate the dorsal immobility response via their effect on cholinergic systems in the central nervous system. © 1990.
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页码：77 / 80
页数：4
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