THE CONTRIBUTION OF O-6-METHYLGUANINE AND METHYLPHOSPHOTRIESTERS TO THE CYTO-TOXICITY OF ALKYLATING-AGENTS IN MAMMALIAN-CELLS

被引:21
作者
HALL, J [1 ]
KATAOKA, H [1 ]
STEPHENSON, C [1 ]
KARRAN, P [1 ]
机构
[1] IMPERIAL CANC RES FUND,CLARE HALL LABS,S MIMMS EN6 3LD,ENGLAND
关键词
D O I
10.1093/carcin/9.9.1587
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1587 / 1593
页数:7
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共 29 条
[11]   TRANSFER OF HUMAN GENES CONFERRING RESISTANCE TO METHYLATING MUTAGENS, BUT NOT TO UV IRRADIATION AND CROSS-LINKING AGENTS, INTO CHINESE-HAMSTER OVARY CELLS [J].
KAINA, B ;
VANZEELAND, AA ;
BACKENDORF, C ;
THIELMANN, HW ;
VANDEPUTTE, P .
MOLECULAR AND CELLULAR BIOLOGY, 1987, 7 (05) :2024-2030
[12]   ADAPTIVE RESPONSE TO ALKYLATING-AGENTS INVOLVES ALTERATION INSITU OF O6-METHYLGUANINE RESIDUES IN DNA [J].
KARRAN, P ;
LINDAHL, T ;
GRIFFIN, B .
NATURE, 1979, 280 (5717) :76-77
[13]   COMPLEMENTATION OF SENSITIVITY TO ALKYLATING-AGENTS IN ESCHERICHIA-COLI AND CHINESE-HAMSTER OVARY CELLS BY EXPRESSION OF A CLONED BACTERIAL-DNA REPAIR GENE [J].
KATAOKA, H ;
HALL, J ;
KARRAN, P .
EMBO JOURNAL, 1986, 5 (12) :3195-3200
[14]   REGULATION AND EXPRESSION OF THE ADAPTIVE RESPONSE TO ALKYLATING-AGENTS [J].
LINDAHL, T ;
SEDGWICK, B ;
SEKIGUCHI, M ;
NAKABEPPU, Y .
ANNUAL REVIEW OF BIOCHEMISTRY, 1988, 57 :133-157
[15]  
MANIATIS T, 1982, MOL CLONING LABORATO
[16]   METHYL PHOSPHOTRIESTERS IN ALKYLATED DNA ARE REPAIRED BY THE ADA REGULATORY PROTEIN OF ESCHERICHIA-COLI [J].
MCCARTHY, TV ;
LINDAHL, T .
NUCLEIC ACIDS RESEARCH, 1985, 13 (08) :2683-2698
[17]   INDUCIBLE REPAIR OF O-ALKYLATED DNA PYRIMIDINES IN ESCHERICHIA-COLI [J].
MCCARTHY, TV ;
KARRAN, P ;
LINDAHL, T .
EMBO JOURNAL, 1984, 3 (03) :545-550
[18]   ROLE OF DEOXYNUCLEOSIDE TRIPHOSPHATE POOLS IN THE CYTO-TOXIC AND MUTAGENIC EFFECTS OF DNA ALKYLATING-AGENTS [J].
MEUTH, M .
SOMATIC CELL GENETICS, 1981, 7 (01) :89-102
[19]   EXPRESSION OF A BACTERIAL GENE IN MAMMALIAN-CELLS [J].
MULLIGAN, RC ;
BERG, P .
SCIENCE, 1980, 209 (4463) :1422-1427
[20]   SELECTION FOR ANIMAL-CELLS THAT EXPRESS THE ESCHERICHIA-COLI GENE CODING FOR XANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE [J].
MULLIGAN, RC ;
BERG, P .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (04) :2072-2076