NOVEL SYNTHESIS OF INDOLES VIA PALLADIUM-CATALYZED REDUCTIVE N-HETEROCYCLIZATION OF ORTHO-NITROSTYRENE DERIVATIVES

被引：55

作者：

AKAZOME, M ^{[1
]}

KONDO, T ^{[1
]}

WATANABE, Y ^{[1
]}

机构：

[1] KYOTO UNIV, FAC ENGN, DEPT HYDROCARBON CHEM, SAKYO KU, KYOTO 60601, JAPAN

来源：

CHEMISTRY LETTERS | 1992年 / 05期

关键词：

D O I：

10.1246/cl.1992.769

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Indole derivatives were readily prepared from the reductive N-heterocyclization of omicron-nitrostyrene derivatives in the presence of a catalytic amount of PdCl2(PPh3)2- SnCl2 under carbon monoxide pressure (20 kg/cm2) at 100-degrees-C for 16 h. With omicron-nitrostibene, 2-phenylindole was obtained in 75% yield.

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页码：769 / 772

页数：4

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