INVERSE RELATIONSHIP BETWEEN THE FLAGELLA FORMATION AND PRODIGIOSIN SYNTHESIS IN SERRATIA-MARCESCENS

Treatment by polymyxin B sulfate and ethylenediaminetetraacetate separated a 40 kilodalton (kDa) protein from the nonpigmented Serratia marcescens and even from the nonpigmented bacteria of the pigmented strains, whereas the same treatment separated the 100 kDa protein associated with the pigment formation from the pigmented bacteria. Lysozyme treatment separated the 100 kDa and/or 40 kDa proteins correlated with the pigment level. The 40 kDa protein was not an outer membrane protein but a flagellin. These results suggest that the flagella formation was inversely related with the pigment formation. © 1990, The Japanese Society of Clinical Pharmacology and Therapeutics. All rights reserved.