A NOVEL 12-MEMBERED TRIAZAOXAMACROCYCLE-N,N',N''-TRIACETIC ACID INDICATOR FOR COLORIMETRIC DETERMINATION OF CALCIUM

被引：8

作者：

BARTSCH, RA ^{[1
]}

CHAPOTEAU, E ^{[1
]}

CZECH, BP ^{[1
]}

KRZYKAWSKI, J ^{[1
]}

KUMAR, A ^{[1
]}

ROBISON, TW ^{[1
]}

机构：

[1] MILES INC,DIV DIAGNOST,TARRYTOWN,NY 10591

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 17期

关键词：

D O I：

10.1021/jo00069a034

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of a novel chromogenic triazaoxamacrocycle bearing three acetic acid groups and a 2,4,6-trinitroanilino chromophore, for generation of a spectrophotometric response, is described. As determined by potentiometric titration conducted in water, tetraionizable chromoionophore 4 forms a rather weak 1:1 complex with calcium (K(s) = 9.5 X 10(2) M-1) but exhibits very high selectivity for Ca2+ over Mg2+ at neutral pH. Cation responses at pH 7.0, 8.0, 9.0, and 10.0 are determined. The response of 4 to calcium is linear from 2 x 10(-5) to 1 x 10(-4) M Ca2+.

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收藏

页码：4681 / 4684

页数：4

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